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Gordon Keller, PhD

McEwen Stem Cell Institute, University Health Network, Canada

Gordon Keller is Director of the McEwen Stem Cell Institute at the University Health Network and Professor in the Department of Medical Biophysics at the University of Toronto. He is internationally recognized for his contributions to our understanding of the directed differentiation of human pluripotent stem cells (hPSCs) in culture. Using developmental biology-guided approaches, his lab has successfully generated a broad spectrum of cells from hPSCs, including most cell types found in the human heart and the majority of lineages that make up the human hematopoietic system. The findings from this work have provided the first comprehensive maps of human cardiac and hematopoietic development and, importantly, have demonstrated that key lineage decisions are made early, at the onset of mesoderm induction. His current research efforts are focused on translating these advances to the development of new cell therapies to treat cardiovascular and hematological diseases.



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