CiRA, Kyoto University, Japan
Akitsu Hotta obtained his Ph.D. in 2006 from Nagoya University by studying transgenic chicken to produce therapeutic antibodies in their eggs. As a postdoctoral fellow, he joined Dr. James Ellis’ laboratory at Toronto and developed the EOS pluripotency reporter to isolate reprogrammed iPS cells. In 2010, he joined CiRA and started his laboratory. Since then, he demonstrated that CRISPR-Cas genome editing could be utilized to repair genetic mutations of Duchenne muscular dystrophy in iPSCs. In addition, he developed a way to escape the immune rejection of iPSCs from T cells and NK cells by adapting CRISPR genome editing. He continues to strive to develop novel genetic tools to realize iPS cell and gene therapies for genetic diseases.
INSIGHTS INTO DISEASE MECHANISMS FROM STEM CELL RESEARCH
Thursday, June 12, 2025
2:00 PM – 3:30 PM HK Time