Innovation Showcases
Differentiating human pluripotent stem cells (hPSCs) into neuronal cells is a crucial step in neurological research. While lentiviral delivery of the transcription factor neurogenin-2 (NGN2) is widely used to accelerate this process, it comes with challenges such as genomic integration risks, variability, and labor-intensive steps. In this talk, we introduce an integration-free, mRNA-lipid nanoparticle (LNP) system designed for the efficient and reproducible generation of highly pure neurons: STEMdiff™-TF Forebrain Induced Neuron Differentiation Kit. Attendees will learn how this method enables rapid neuron differentiation with high purity and functional maturation, promotes sustained synaptic activity, simplifies workflows, and reduces common challenges associated with viral methods. With functional characterization confirming this system’s capability to generate physiologically relevant forebrain neurons, researchers can access a reliable platform for drug discovery. Join us to discover how STEMdiff™-TF can accelerate your neuronal research while providing a user-friendly approach to hPSC differentiation.