Innovation Showcases
Neurological and psychiatric disorders remain the leading cause of illness and disability worldwide, posing a major challenge to global health. In response, the field is rapidly evolving driven by transformative tools such as induced pluripotent stem cell (iPSC)-derived 2D and 3D models, which offer unprecedented opportunities to study disease mechanisms and identify therapeutic targets.
Next-generation high-density microelectrode arrays (HD-MEAs), as provided by the MaxOne and MaxTwo platforms, offer a powerful, non-invasive method for investigating neural morphology, maturation, connectivity, and functional dynamics in both healthy and disease-specific iPSCs-derived models.
In this Innovation Showcase, we will be joined by leading researchers to spotlight the power of next-generation electrophysiology in advancing neuropsychiatric disease modeling. Together, we will explore how HD-MEAs are enabling detailed functional characterization of diverse neuron subtypes providing further insights into signaling pathways driving neuronal fate. In addition, novel cutting-edge electrophysiological strategies to study gene dysfunctions linked to psychiatric conditions will be presented.
These approaches are not only reshaping how we model complex brain disorders, but also accelerating progress toward more precise therapies.