DISEASE MODELING AND DRUG DISCOVERY (DMDD)

(T1001) INVESTIGATING THE IMPACT OF STRESS AND BLOOD-BRAIN BARRIER DYSFUNCTION ON ALZHEIMER’S DISEASE PATHOLOGY USING 2D AND 3D MODELS

(T1002) Investigating the Neurotoxicity Mechanism of Sodium Chlorate Using iPSC-Derived Dopaminergic Neurons and Zebrafish

(T1003) INVESTIGATING THE ROLE OF THE EXTRACELLULAR VESICLES ENRICHED PROTEINS FOR SARS-COV-2 PATHOGENESIS IN HUMAN RESPIRATORY ORGANOIDS

(T1004) INVESTIGATING THE USE OF ALLELE-SPECIFIC GENOME EDITING IN A RARE AUTOSOMAL DOMINANT FORM OF BLINDNESS

(T1005) Investigation on mechanism of AMPK antiviral function in EV-A71 infection

(T1006) IPSC MODELS OF ALPK3 CARDIOMYOPATHY REVEAL DYSREGULATION OF PROTEIN QUALITY CONTROL NETWORKS

(T1007) IPSC-DERIVED TUBULOIDS: A HIGH-CONTENT SCREENING PLATFORM FOR UMOD VARIANTS IN KIDNEY DISEASE

(T1008) iSCORE-PD: an isogenic stem cell collection to research Parkinson’s Disease

(T1009) LABEL-FREE FUNCTIONAL ANALYSIS FOR THE SCREENING OF IPSC-DERIVED NEURAL ORGANOID RESPONSE TO NEUROACTIVE COMPOUNDS

(T1010) LARGE SCALE ANALYSIS OF LOSS OF CHROMOSOME Y IN HUMAN PLURIPOTENT STEM CELLS: IMPLICATIONS FOR TURNER SYNDROME AND RIBOSOMOPATHIES

(T1011) Large-scale generation of iNK and CAR iNK cells from CD34+ hematopoietic stem and progenitor cells for adoptive immunotherapy

(T1012) LINE-1 MEDIATED NEUROINFLAMMATION IN DIRECTLY CONVERTED ALZHEIMER'S DISEASE NEURONS

(T1013) Liver hepatobiliary progenitors-derived organoids cultured in decellularized extracellular hydrogel for Biliary Atresia modeling

(T1014) LOCAL HETEROCHROMATIN MITIGATES THE IMPACT OF A TRANSPOSABLE ELEMENT INSERTION CAUSING A NEURODEGENERATIVE DISORDER

(T1015) Long-term correction of hemophilia A through AAVS1-targeted integration of a functionally enhanced FVIII gene using Cas9 nickase in patient-derived iPSCs

(T1016) CASPASE3/GSDMD COUPLED SUB-APOPTOSIS RECONSTRUCT NUCLEAR ARCHITECTURE TO GUIDE STEM CELL NEUROGENESIS

(T1016) MASLD AND FIBROSIS ANALYSIS MODEL COMBINING SINGLE-CELL OMICS AND MULTI-DONOR ORGANOIDS

(T1017) MECHANICAL TENSILE LOADING AND STRESSING ALTER ECM DEPOSITION OF HUMAN MENISCUS TISSUE RESIDENT PROGENITOR CELLS

(T1018) MESENCHYMAL STROMAL CELL THERAPY: A PROMISING APPROACH TO COMBAT AGE-INDUCED SARCOPENIA

(T1019) METABOIC DYSFUNCTION-ASSOCIATED STEATOHEPATITIS MODELING WITH HUMAN LIVER MICROENVIRONMENT-INCORPORATED ORGANOIDS

(T1020) METABOLIC DYSREGULATION IN BONE MARROW MESENCHYMAL STEM CELLS: IMPLICATIONS FOR OSTEOPOROTIC FRAGILITY IN WOMEN

(T1021) METABOLIC REPROGRAMMING IN ALZHEIMER’S DISEASE DISRUPTS NEURONAL RESILIENCE THROUGH DYSREGULATION OF ALTERNATIVE SPLICING

(T1022) METABOLITE-BASED THERAPEUTICS FOR FRAGILE X SYNDROME UTILIZING HUMAN PLURIPOTENT STEM CELLS

(T1023) Mice with 16p11.2 deletion and duplication show alterations in biological processes associated with white matter

(T1024) MICROGLIA REPLACEMENT EXTENDS SURVIVAL BY REMODELING NEURAL COMMUNICATION NETWORKS IN A MOUSE MODEL OF ALS

(T1026) Microglial TMEM119 is involved in aggregated Aβ clearance in amyloid-β depositing mice

(T1027) MINIATURE ENGINEERED HEART TISSUES FROM HUMAN IPSC-CARDIOMYOCYTES ON A HYPOXIA ON-A-CHIP PLATFORM

(T1028) MIXED EFFECTS MODEL TO UNDERSTAND SOURCES OF CONTRACTILE AND MORPHOLOGICAL HETEROGENEITY IN HIPSC-CMs

(T1029) MODELING CDKL5 DEFICIENCY DISORDER USING CEREBRAL ORGANOIDS REVEALS HUMAN-ENRICHED CELLULAR DEFICITS

(T1030) Modeling Fragile X Syndrome in Human Hippocampal Organoids Reveals Altered Developmental Trajectories and FMRP Binding Dynamics

(T1031) MODELING HEREDITARY SENSORY AND AUTONOMIC NEUROPATHY TYPE IV (HSAN IV) USING HUMAN DRG ORGANOIDS DERIVED FROM PATIENT INDUCED PLURIPOTENT STEM CELLS

(T1032) MODELING HUMAN HEMATOPOIETIC AND CARDIAC CO-DEVELOPMENT IN hPSC-DERIVED ORGANOIDS

(T1033) Modeling Recessive Dystrophic Epidermolysis Bullosa (RDEB) Using Patient-Specific iPSC-Derived Skin Organoids and CRISPR/Cas9 Gene Editing

(T1034) MODELLING DMV FORMATION IN SARS-COV-2-INFECTED AIRWAY EPITHELIAL CELLS DERIVED FROM HUMAN PLURIPOTENT STEM CELLS

(T1035) MODELLING GENETIC PARKINSON’S DISEASE IN A MULTIPLEXED MOSAIC ORGANOID SYSTEM

(T1036) Modelling particulate matter interaction in the alveolar niche using a chemically defined multi-cell type organoid system using human induced pluripotent stem cells.

(T1037) MODULAR IN VITRO PLATFORM FOR MIMICKING THE MECHANICAL FORCES INDUCED ON TISSUES IN HEALTH AND DISEASE

(T1038) Modulating the fetal environment with extracellular vesicles: a minimally invasive approach to treating congenital disorders

(T1039) Molecular Mechanisms of Stress Resilience: Novel Therapeutic Strategies for Delaying Aging and Neuroprotection

(T1040) SSEA3 AND CD105 POSITIVITY ARE ASSOCIATED WITH THE TREATMENT POTENCY OF HUMAN NEURAL CREST-DERIVED NASAL TURBINATE STEM CELLS FOR ALZHEIMER'S DISEASE

(T1041) Motor neuron-specific DLC1-i1 deficiency leads to neuromuscular defects in spinal muscular atrophy

(T1042) MOUSE LIVER ASSEMBLOIDS RECAPITULATE PERIPORTAL MESOSCALE ARCHITECTURE AND MODEL BILIARY FIBROSIS IN VITRO

(T1043) MPOX VIRUS OPG175 NEGATIVELY REGULATES VIRAL REPLICATION VIA CONTROLLING WNT SIGNALING

(T1044) MULTI-OMICS ANALYSIS REVEALS ISCHEMIC STROKE-LIKE FEATURES IN MATURED HIPSC-DERIVED NEUROSPHEROIDS AFTER OXYGEN-GLUCOSE DEPRIVATION/REOXYGENATION

(T1045) MULTIOMICS MAPPING AND CHARACTERIZATION OF CELLULAR SENESCENCE IN AGING HUMAN SKELETAL MUSCLE UNCOVERS A NOVEL SENOTHERAPEUTIC FOR SARCOPENIA

(T1046) Multiomics study to elucidate the molecular pathogenesis of choledochal cysts

(T1047) MUTANT HUNTINGTIN DISRUPTS GLOBAL DNA METHYLATION IN HUMAN iPSC-DERIVED CEREBRAL ORGANOIDS

(T1048) Nanotechnologies in target treating Preterm Birth and Premature Ovarian Failures

(T1049) NERVE GROWTH FACTOR-DERIVED PEPTIDES ACCELERATE OSTEOGENESIS OF HUMAN BONE MARROW MESENCHYMAL STEM CELLS AND PROMOTE BONE FORMATION

(T1050) NEURAL NETWORK DYSREGULATION IN SPORADIC ALZHEIMER'S DISEASE ASTROCYTE ENRICHED BRAIN ORGANOIDS

(T1051) Neural Plasticity Changes Induced by Serotonergic Psychedelic Compounds in Cortical Organoids

(T1052) NEUREXIN1 KNOCKOUT IPSC-DERIVED NEURONS DISPLAY HETEROGENOUS TRANSCRIPTOMIC EFFECTS ACROSS DIFFERENT GENETIC BACKGROUNDS

(T1053) NEUROMUSCULAR ORGANOIDS AS A HUMAN IN VITRO MODEL FOR SARCOPENIA

(T1054) NEXT-GENERATION ELECTROPHYSIOLOGY FOR FUNCTIONAL CHARACTERIZATION OF HUMAN NEURAL ORGANOIDS AND ASSEMBLOIDS

(T1055) Novel Pathogenesis of Diamond-Blackfan Anemia Explored Through Regulation of Proteostasis.

(T1056) OPTIMAL ADMINISTRATION METHOD FOR MRNA-LNP DELIVERY TO THE HEART

(T1057) ORGANOID-BASED NEUTRALIZATION ASSAYS REVEALED A DISTINCTIVE PROFILE OF SARS-CoV-2 ANTIBODIES AND RECAPITULATED THE REAL-WORLD EFFICACY

(T1058) Ovarian Cancer Patient-Derived Organoids as a Model for Recapitulating Genetic Profiles and Evaluating Drug Response: A Pilot Study

(T1059) Oxytocin promotes elongation of hair peg-like sprouting in hair follicle organoids

(T1060) PANCREATIC HYPOPLASIA AND ISLET DYSFUNCTION IN RFX6 MUTATION-ASSOCIATED DIABETES: REVEALING MECHANISMS THROUGH IPSC-DERIVED ISLET ORGANOIDS

(T1061) PATIENT-DERIVED CELLULAR PLATFORM IN MODELLING INFLAMMATORY PROCESS OF LUPUS NEPHRITIS

(T1062) Patient-specific iPSC-derived hepatic organoids as model for mRNA-based gene therapy in farnesoid-X receptor (FXR) deficiencies

(T1063) PD-L1 Overexpressing mesenchymal stem cells and their derived extracellular vesicles in the treatment of type 1 diabetes

(T1064) PERSONALIZED IPSC-DERIVED ORGANOIDS FOR HUMAN PANETH CELL MODELING

(T1065) PHARMACEUTICAL RESEARCH OF RESPIRATORY SYNCYTIAL VIRUS USING HUMAN IPS-DERIVED RESPIRATORY ORGANOIDS

(T1066) PLATELET-RICH-PLASMA IMMUNOMODULATORY EFFECTS ON T CELLS IS DEPENDENT UPON DOSAGE AND TIMING OF INITIAL EXPOSURE

(T1067) PNPLA3 POLYMORPHISM AS A POSSIBLE DETERMINANT OF BILE ACIDS DYSREGULATION AND MASLD PROGRESSION

(T1068) POPULATION-SPECIFIC TRANSCRIPTOMIC AND MOLECULAR INSIGHTS INTO PRPF31-ASSOCIATED RETINITIS PIGMENTOSA USING RETINAL ORGANOIDS

(T1069) PRECISION-CUT LUNG SLICE CULTURE FOR VALIDATING PRO-FIBROTIC AND PRO-RESOLVING PROTEINS IN HUMAN LUNG FIBROSIS

(T1070) PRE-CLINICAL IN VITRO EFFICACY OF ENGINEERED MESENCHYMAL STEM/STROMAL CELLS EXPRESSING SOLUBLE ACE2 DECOYS FOR ELIMINATION OF SARS-CoV-2 INFECTION

(T1071) PRIMARY EPITHELIAL LUNG ORGANOIDS DERIVED FROM THE HUMAN AMNIOTIC FLUID AS PERSONALISED MODEL FOR CONGENITAL DIAPHRAGMATIC HERNIA

(T1072) Probing the pathology of amyotrophic lateral sclerosis using induced neural stem cells obtained by direct lineage reprogramming

(T1073) PROGERIN-DRIVEN CELLULAR AGING AND NEURODEGENERATION IN DOPAMINERGIC NEURONS: AN IPSC-BASED MODEL FOR PARKINSON’S DISEASE RESEARCH

(T1074) PT1A AND SORAFENIB COMBINATION TREATMENT EXERTS SYNERGISTIC ANTI‑HEPATOCELLULAR CARCINOMA EFFECT THROUGH RNA M6A METHYLATION MODIFICATION

(T1075) RAPID ANTIVIRAL SCREENING IN TROPHOBLAST CELLS AGAINST EMERGING VIRUSES

(T1076) Rapid iPSC-Derived Neuromuscular Junction Model Uncovers Motor Neuron Dominance in Amyotrophic Lateral Sclerosis Cytopathy

(T1077) RARE DISEASE MODELLING USING HUMAN INDUCED PLURIPOTENT STEM CELL-DERIVED CARDIOMYOCYTE MODELS IN 3D FN-SILK SCAFFOLDS

(T1078) Reciprocal enhancement of SARS-CoV-2 and influenza virus replication in human pluripotent stem cell-derived lung organoids

(T1079) RNA THERAPEUTICS FOR EARLY-ONSET FAMILIAL ALZHEIMER’S DISEASE USING HUMAN STEM CELL MODELS

(T1080) ROLE OF ZNF808 IN HUMAN PANCREATIC CELL FATE SPECIFICATION

(T1081) Safety and Efficacy of Mesenchymal Stromal Cells Mitochondria Transplantation as a Cell-Free Therapy for Osteoarthritis

(T1082) SEX-SPECIFIC REGULATION OF WNT SIGNALING AND INFLAMMATION IN OSTEOGENIC DIFFERENTIATION OF HUMAN AORTIC VALVE INTERSTITIAL CELLS

(T1083) SINGLE-CELL RNA SEQUENCING OF FELINE MAMMARY TUMOR ORGANOIDS REVEALS DIFFERENT GENE PROFILES AND PATHWAYS BETWEEN BASAL AND LUMINAL TYPES.

(T1084) Single-cell transcriptomic analysis reveals distinct cellular responses among cortical progenitors and neurons in human brain organoid modeling fetal hypoxic brain injury

(T1085) SINGLE-CELL TRANSCRIPTOMIC ROADMAP TO HUMAN INDUCED HEPATOCYTE-LIKE CELLS REVEALS A LIVER DEVELOPMENTAL TRAJECTORY DURING LINEAGE REPROGRAMMING

(T1086) SINGLE-CELL TRANSCRIPTOMICS REVEALS REDUCED MOTOR NEURONS AND AXONAL OUTGROWTH IN NEUROMUSCULAR ORGANOIDS GENERATED FROM SPINAL MUSCULAR ATROPHY PATIENTS’ URINE DERIVED IPSCS

(T1087) SMA PATIENT-SPECIFIC IPSC-DERIVED MOTOR NEURONS EXERT ELECTROPHYSIOLOGICAL, MOLECULAR, AND METABOLIC ABNORMALITIES

(T1088) SMALL EXTRACELLULAR VESICLES (SEV) FROM GLYCOLYTICALLY ACTIVATED MESENCHYMAL STEM/STROMAL CELLS PROMOTE CHONDROPROTECTION IN VITRO AND CARTILAGE REGENERATION IN VIVO

(T1089) SMALL EXTRACELLULAR VESICLES FROM METABOLICALLY REPROGRAMMED MESENCHYMAL STEM/STROMAL CELL AS A POTENTIAL IMMUNOSUPPRESSIVE MECHANISM FOR INFLAMMATORY AND AUTOIMMUNE DISEASES

(T1090) SPINAL CORD ORGANOIDS (SCOS) ARE VALUABLE MODELS FOR DEVELOPMENT AND DISEASES. WE PERFORMED SINGLE-CELL RNA-SEQ ON SCOS (D30–120), REVEALING DIVERSE CELL TYPES AND A DETAILED MOLECULAR ATLAS OVER TIME.

(T1091) STROKE-HEART SYNDROME ON-A-CHIP

(T1092) TARGETING PD-1/PD-L1 PATHWAY FOR IMMUNOTHERAPY AGAINST ZIKA VIRUS INFECTION

(T1093) TARGETING STAT-1 GoF IN INBORN ERRORS OF IMMUNITY: A PATIENT-DERIVED EPSC PLATFORM FOR DRUG DISCOVERY

(T1094) THE IMPORTANCE OF HIGH-DENSITY MICROELECTRODE ARRAYS FOR RECORDING MULTI-SCALE EXTRACELLULAR POTENTIAL AND LABEL-FREE CHARACTERIZATION OF NETWORK DYNAMICS IN IPSC-DERIVED NEURONS

(T1095) THE ROLE OF CRISP3 IN REGULATING ENDOMETRIAL RECEPTIVITY IN REPEATED IMPLANTATION FAILURE

(T1096) THE RS6903956 GENETIC VARIANT CONTIRBUTES TO ENDOTHELIAL DYSFUNCTION VIA HOX-MEIS COOPERATIVE REGULATION OF PHACTR1 IN CORONARY ARTERY DISEASE

(T1097) THE VILLAGE IN A DISH MODEL: A PLATFORM FOR INVESTIGATING IPSC POPULATION DYNAMICS AND DNA DAMAGE RESPONSE

(T1098) THERAPEUTIC EFFICACY OF DANGO TREATMENT ON ALZHEIMER'S DISEASE BRAIN ORGANOIDS DERIVED FROM MULTIPLE PATIENT SOURCES

(T1099) Therapeutic Potential of Extracellular Vesicles in UV-Induced Photoaging

(T1100) THERAPEUTIC POTENTIAL OF HUMAN INDUCED PLURIPOTENT STEM CELL-DERIVED MICROGLIA OVEREXPRESSING INTERLEUKIN-10 IN ALZHEIMER’S DISEASE

(T1101) Therapeutic Proof of Concept Study for the Use of Antisense Oligonucleotides in Kleefstra Syndrome

(T1102) Three-dimensional organoid model derived from stem cells to study and develop treatments for neuromuscular disorders, focusing on spinal cord and muscle integration.

(T1103) TRANSCRIPTOMIC ANALYSIS AND BIOENGINEERED TISSUE MODEL OF DYSTROPHINOPATHY WITH PATIENT-DERIVED IPSC-CARDIOMYOCYTES

(T1104) Transformer-Based Cell Type Prediction Incorporating the Bag Structure of Gene Expression Data

(T1105) Transforming the Storage and Shipment of Tissues & In Vitro Cell Models using Atelerix’s Hydrogel Technology

(T1106) TRANSFORMING THE THERAPEUTIC LANDSCAPE OF PANCREATIC CANCER THROUGH LOCAL DELIVERY OF AN IMMUNE-ACTIVATING SMALL MOLECULE AND CYTOKINE-INDUCED KILLER CELL SYNERGY

(T1107) TRIM28 LINKS TRANSPOSABLE ELEMENT ACTIVATION TO NEURODEVELOPMENTAL DISORDERS: EVIDENCE FROM IPSC-BASED MODELS

(T1108) UBIQUITIN LIGASE RBCK1 MODULATES GLYCOGEN METABOLISM BY ALTERING THE SUBCELLULAR LOCALIZATION OF A GLYCOLYTIC ENZYME

(T1109) Unraveling the Role of Hoxb5 in Hematopoietic Stem Cell Self-Renewal and Differentiation

(T1110) Unraveling the Role of WDR19 Hypomorphic Mutation in Adult-Onset Renal Failure Using hPSC-Derived Kidney Organoids

(T1111) Unveiling Tissue-Specific Transcriptional Adaptations in iPSC-Derived Fibroblasts via Co-Culture Systems

(T1112) Use of antimicrobial nanoparticles for the management of dental diseases

(T1113) USING DIRECTED DIFFERENCIATION TO ESTABLISH A NOVEL NEURAL MODEL OF KABUKI SYNDROME

(T1114) USING IPSC-DERIVED NEURAL PROGENITOR CELLS TO MODEL THE DE NOVO MAX P.ARG60GLN VARIANT UNDERLYING MAX-ASSOCIATED GLOBAL DEVELOPMENT DISORDER

(T1115) Using mitochondria-rich, patient-derived hiPSC-cardiomyocytes to study doxorubicin-induced cardiotoxicity

(T1116) UTILIZING AUTOMATION PLATFORTMS TO ENABLE SCALABLE AND REPRODUCIBLE IPSC GENOME ENGINEERING AND DIFERENTIATION FOR DOWNSTREAM ASSAY DEVELOPMENT AND DISEASE MODELING

(T1117) UTILIZING IPSC MODELS TO INVESTIGATE MAPT MUTATION-INDUCED TAU AGGREGATION AND THERAPEUTIC STRATEGIES

(T1118) Validating functional cardiomyocyte-specific histone-acetylated variant enhancers in human ES-derived Cardiomyocytes using a STARR-seq approach

(T1119) Vascularized Brain Organoid-on-Chip with Functional Vasculature and Blood-Brain Barrier Characteristics

(T1120) VASCULARIZED SKIN ASSEMBLOIDS INTEGRATING IMMUNE SYSTEM: A HUMAN IPSC-DERIVED PLATFORM TO INVESTIGATE ALLERGEN-INDUCED ATOPIC DERMATITIS

(T1360) LOSS OF UBIQUITIN-SPECIFIC PROTEASE 11 ALLEVIATES PULMONARY FIBROSIS IN HUMAN PLURIPOTENT STEM CELL-DERIVED ALVEOLAR ORGANOIDS

(T1361) TARGETING USP11 COUNTERACTS SFTPCI73T-ASSOCIATED PULMONARY FIBROSIS IN HIPSCS-DERIVED ALVEOLAR ORGANOIDS AND IN VIVO MODELS

(T1363) COLLAGEN MATRIX IMPROVES CARDIOMYOCYTE CONTRACTILITY AND MATURITY COMPARED TO FIBRIN IN 3D ENGINEERED HIPSC CARDIAC TISSUE STRIPS

(W1091) A VERSATILE TOOLBOX OF HUMAN IPSC-DERIVED MICROGLIA FOR DISEASE MODELLING, CRISPR SCREENS AND MULTICELLULAR IN VITRO MODELS FOR NEURODEGENERATION DRUG DISCOVERY

(W1092) DEVELOPMENT OF AN AGE-RELATED HEARING LOSS ORGANOID MODEL USING PATIENT-SPECIFIC MIRNA

(W1093) ENGINEERED NEURAL STEM CELL-DERIVED EXTRACELLULAR VESICLES DELIVERING WNT7A-K190A: A NOVEL THERAPEUTIC PLATFORM FOR BLOOD–BRAIN BARRIER RESTORATION

(W1094) Hepatic Organoid-based Model for Severe Fever with Thrombocytopenia Syndrome Virus (SFTSV) Infection

(W1095) Paeoniflorin Combined with Neural Stem Cell Transplantation for Parkinson's Disease: Synergistic Effects of Cell Therapy and Inflammation Regulation

(W1096) A sensitive qPCR method tracking transplanted human iPSC-derived cells in xenotransplantation models for pre-clinical research

(W1097) ANGIOGENESIS PROVIDES A FUNDAMENTAL SUPPORT FOR HOMING OF EXOGENOUSLY INFUSED ALLOGENEIC AD-MSCS TO THE INJURED BRAIN TISSUE POST ACUTE ISCHEMIC STROKE

(W1098) AUTOMATING HIGH-THROUGHPUT SCREENING OF CARDIAC CONTRACTILITY BY ROBOTICALLY CONTROLLED FUNCTIONAL TESTING OF STEM CELL-DERIVED MICRO-TISSUES IN A 96-WELL PLATE FORMAT

(W1099) NOVEL METHOD FOR CELL REJUVENATION VIA MRNA-BASED PARTIAL REPROGRAMMING

(W1100) DECIPHER TEMPORAL CONTROL OF GENE REGULATION DURING HEALTHY AND DISEASED THYMIC ORGANOGENESIS USING 22q11DS HUMAN INDUCED PLURIPOTENT STEM CELL MODEL

(W1101) DISENTANGLING NETWORK DYSFUNCTION PHENOTYPES IN LITHIUM-RESPONSIVE BIPOLAR DISORDER & SCHIZOPHRENIA

(W1103) Modelling Injury Specific Lung Repair Using hIPSC-derived Immune Competent Alveolar Organoids

(W1104) MODERATE SCALE MANUFACTURING OF HUMAN IPSC-DERIVED IMMUNE CELLS

(W1105) Organoid Fibrosis Model: Accelerating the Research and Development of Therapeutics for Fibrotic Diseases

(W1106) RAPID DEVELOPMENT FRAMEWORK FOR THE GENERATION OF PATIENT SPECIFIC, RARE DISEASE IPSCS: THE ZTTK CASE STUDY

(W1107) RECAPITULATING HEREDITARY ANGIOEDEMA USING A PERSONALIZED EXPANDED POTENTIAL STEM CELL (EPSC) PLATFORM: DEMONSTRATING SIGNALS OF LIVER DISEASE AMONG HEPATOCYTES DIFFERENTIATED FROM PATIENT EPSC

(W1108) "Derivation of liver stem cells to dissect molecular pathways for non-alcoholic fatty liver disease"

(W1109) Characterization And Validation of Human IPSC-Derived Nociceptors for Pain Modeling

(W1110) CHARACTERIZING THE ROLE OF PUTATIVE ENHANCERS IN RETINAL DISEASES USING HUMAN RETINAL ORGANOIDS

(W1111) Choroid Plexus Organoids as a Model for Investigating Glucose Transport in GLUT1 Deficiency Syndrome

(W1112) CRISPR MEETS OPTI-OX: NEXT-GENERATION HUMAN NEURAL CELL MODELS FOR NEUROSCIENCE RESEARCH AND DRUG DISCOVERY

(W1113) CRISPR-ENHANCED IPSC DIFFERENTIATION AND ENRICHMENT FOR THE ASSEMBLY OF NOVEL BIOPRINTED RETINAL MODELS IN AMD RESEARCH

(W1115) Engineering approaches to enhance the therapeutic potential of extracellular vesicles from mesenchymal stem cells

(W1116) GENERATION OF MACROPHAGE-INTEGRATED 3D CARDIAC SPHEROIDS FROM HUMAN INDUCED PLURIPOTENT STEM CELLS

(W1117) Histone Lactylation Regulating VISTA+MDSC to Mediate Immune Escape of Intrahepatic Cholangiocarcinoma

(W1118) NOVEL VASCULARIZED NEURAL SPHEROIDS FACILITATE REPAIR IN THE SPINAL CORD INJURY

(W1119) OSTEOBLAST AND OSTEOCLAST DIFFERENTIATION IN GAUCHER DISEASE: INSIGHTS INTO BONE ABNORMALITIES

(W1120) Pre-clinical targeting of cancer stem cells via ADAR1 inhibition with Rebecsinib in TNBC

(W1121) ENHANCED DRUG CLASSIFICATION USING MACHINE LEARNING WITH MULTIPLEXED CARDIAC CONTRACTILITY ASSAYS

(W1122) TARGETING THE RNA-BINDING PROTEIN HUD IN HUMAN IPSCS TO CONTROL ALS DISEASE

(W1123) A novel form of Angiopoietin 1 as a priming agent to enhance the therapeutic efficacy of mobilized human peripheral blood stem cells in treating ischemic cardiovascular disease

(W1124) Cardiac Protective Strategy Against Doxorubicin-induced Cardiac Toxicity

(W1125) CHRONIC FOS ACTIVATION AS A DRIVER OF MUSCLE STEM CELL DYSFUNCTION IN DUCHENNE MUSCULAR DYSTROPHY

(W1126) Cooperative antibacterial effect using lactonase Est816-Ag polymer nanocomposite

(W1127) Deciphering cellular metabolisms of glia in APOE4 carriers of Alzheimer's disease brain using hiPSCs to identify small molecule targets for therapeutics

(W1128) DECODING ADENOMYOSIS PATHOGENESIS USING AN ASSEMBLOID MODEL

(W1129) DERINAT PROMOTES ANAGEN ENTRY BY INHIBITING Ca²⁺ SIGNALING

(W1130) Derivation of Macrophages from Porcine Expanded Potential Stem Cells for Studying Host-pathogen Interactions and Anti-virus Discovery

(W1131) DEVELOPING CELL BASED BIOASSAYS FOR CLINICAL TRIALS- THE USE OF PATIENT DERIVED INDUCED NEURONS TO STUDY AUTOPHAGY IN THE FELL-HD TRIAL

(W1132) Differential effects of mononuclear phagocytes from healthy Individuals and age-related macular degeneration patients on the transcriptome of hESC-derived retinal pigment epithelium cells.

(W1133) Establishment of a rat model suitable for human-rat xenotransplantation and humanized liver

(W1134) Health Conferred By Epithelial Cells and Their Role In Paraphagy Promoted Cholesterol Clearance and Lipid Metabolism During Epididymal Sperm Maturation

(W1135) Human MSCs ameliorate Extraocular Myopathy in Thyroid Eye Disease

(W1136) Identification of Stress-Resilience Gene as a Novel Target of Alzheimer’s disease

(W1137) IGF1 Drives Neural Precursor Expansion and Inhibitory Neuron Specification via mTOR Translational Control: Insights into Tuberous Sclerosis

(W1138) Inducing Maturation of Human Ameloblasts for Tooth Regeneration and Disease Modeling of Amelogenesis Imperfecta

(W1139) INDUCTION OF PROINFLAMMATORY CYTOKINE RELEASE FROM HUMAN PLURIPOTENT STEM CELL-DERIVED MACROPHAGES BY EXOSOMAL ORF3A DERIVED FROM SARS-COV-2-INFECTED CELLS

(W1140) INVESTIGATING THE SYNERGISTIC EFFECTS OF QUERCETIN AND VITAMIN C ON HUMAN CHONDROPROGENITORS: A CELLULAR AND MOLECULAR APPROACH

(W1141) MESENCHYMAL STEM CELLS FROM PERINATAL TISSUES PROMOTE DIABETIC WOUND HEALING VIA PI3K/AKT ACTIVATION

(W1143) Modelling tumour microenvironment by assembloids fusion of immune vascular organoids and patient derived organoids

(W1144) Polycystic Kidney Organoids for Disease Modelling and Drug Screening

(W1145) REVERSAL OF CONTRACTILE DEFECTS IN ENGINEERED HUMAN TISSUE MODELS OF HEART FAILURE WITH PRESERVED EJECTION FRACTION (HFPEF) LEADS TO FIRST-IN-HUMAN GENE THERAPY CLINICAL TRIAL

(W1146) Selective vulnerability of cerebral vascular smooth muscle cells to NOTCH3 variants in an iPSC model of genetic small vessel disease CADASIL and a novel therapeutic target

(W1147) SINGLE CELL ANALYSIS OF HUMAN IPSC-DERIVED NEURONS CARRYING THE ALZHEIMER DISEASE-ASSOCIATED APPV717I MUTATION AFTER LONG-TERM ENGRAFTMENT IN THE ADULT MOUSE FOREBRAIN

(W1148) THE CARDIOTOXICITY OF METABOLIC SYNDROME VLDL IN INDUCING CARDIOMYOCYTE MITOCHONDRIA DYSFUNCTION

(W1149) THE DELETERIOUS IMPACTS OF INTERFERON-GAMMA AND NEUROTOXIN QUINOLINIC ACID ON CELLULAR HEALTH OF SVZ NEURAL STEM CELLS AND CONSEQUENCES FOR REGENERATION

(W1150) UNLOCKING THE POTENTIAL OF BRAIN ORGANOIDS FOR UNDERSTANDING AND TREATING NEURODEVELOPMENTAL DISORDERS

(W1151) ADSC-CM have scar-suppressing effect in human keloid transplant mouse model

(W1152) ALMS1 MUTATION IMPAIRS CILIARY DISASSEMBLY AND PROMOTES CELL CYCLE EXIT IN ALSTROM SYNDROME BRAIN ORGANOIDS

(W1153) Analysis of microRNA-mediated Gene Regulation in Various Cell Lines upon Exposure to LDL and Latex Particles

(W1154) AUTOMATED CARDIAC ORGANOID WORKFLOW ON CELLXPRESS.AI WITH INTEGRATED END POINT ASSAY AND DEEP LEARNING IMAGE ANALYSIS

(W1155) BULK AND SINGLE CELL TRANSCRIPTOMIC ANALYSIS OF HUMAN IPSC-DERIVED SENSORY NEURONS AS A MODEL FOR NON-OPIOID PAIN THERAPEUTIC DRUG DISCOVERY

(W1156) CHRONIC ETHANOL EXPOSURE DRIVES AMYLOID BETA DEPOSITION AND IMPAIRED NEURONAL MATURATION IN HUMAN IPSC-CORTICAL NEURONS AND CEREBRAL ORGANOIDS

(W1157) Construction of Tissue Deried Kidney-Derived Organoids and Disease Modeling

(W1158) CORE MODELS: NEXT-GENERATION CEREBRAL ASSEMBLOIDS FOR BRAIN CANCER MODELING AND DRUG DISCOVER

(W1159) DECIPHERING THE MOLECULAR BASIS OF HEREDITARY ULNAR DEFICIENCY INDUCED BY COMPLEX STRUCTURAL VARIANTS

(W1160) Deciphering the Regenerative Capacities of UC-MSCs and BM-MSCs: A Focus on Cytokine and Fibrosis-Related miRNA Profiles

(W1161) DECREASED COMPLEXITY AND ACTIVITY OF HUMAN CORTICAL NEURONS DERIVED FROM PATIENT WITH DYRK1A MUTATION

(W1162) Development of a Non-Human Primate Model Mimicking Human Perforator Infarction for Therapeutic Applications

(W1163) DEVELOPMENT OF HUMAN IPSC-DERIVED HEPATOCYTES FOR DRUG DISCOVERY, TRANSLATIONAL RESEARCH AND TOXICITY TESTING

(W1164) Divergent lineage trajectories and genetic landscapes in human gastric intestinal metaplasia organoids associated with early neoplastic progression

(W1165) Efficient Production of Cardiomyocytes in 2D en 3D: Wnt and Insulin Enhance Proliferation and Inhibit Maturation of Human iPSC-derived Cardiomyocytes via TCF and FOXO Signaling

(W1166) Feasibility of 3D human induced pluripotent stem cell-derived osteoblast using Air-Liquid interface method for spinal fusion in a rat model; Preliminary report

(W1167) GENE TARGETING OF NOS1AP IN HUMAN IPSC-DERIVED CARDIOMYOCYTES FROM PATIENTS WITH LONG QT SYNDROME TYPE 1

(W1168) GENERATION OF LGE-COMMITTED NEURAL PROGENITOR CELLS WITH AFFINITY TOWARD DRD2+ MEDIUM SPINY NEURON POPULATION FROM HUMAN STEM CELLS USING A NOVEL SMALL MOLECULE-BASED RECIPE

(W1169) HSP70 and miR-22-3p in Mesenchymal Stem Cell-Derived Extracellular Vesicles: Modulating Th2 Immunity in Atopic Dermatitis

(W1170) HUMAN BREAST MILK PRESERVES FATTY TRANSPORT AND INTESTINAL INTEGRITY IN MODELING NECROTIZING ENTEROCOLITIS USING HUMAN SMALL INTESTINAL ORGANOIDS

(W1171) HUMAN TROPHOBLAST ORGANOID-BASED INFECTION MODELS REVEAL DIFFERENTIAL RESPONSE TO HEPATITIS E VIRUS GENOTYPES

(W1172) Increased Natural Killer Resistance in p53-deficient Osteosarcoma and Mesenchymal Stem Cells due to Upregulated NF-κB-IFNβ-HLA Signalling

(W1173) INNOVATIVE IN VITRO TERATOGENICITY MODELS: FROM MOUSE TO HUMANS

(W1174) INNOVATIVE WORKFLOW FOR DRUG RESPONSE STUDIES ON SINGLE 3D CELL MODELS COMBINING SPHEROONE and INCUCYTE.

(W1175) Integration of iPSC-derived microglia into cerebral organoid for studying neuroimmunology

(W1176) Interplay between IRE1α and cardiac excitation-contraction coupling in stem cells-derived cardiomyocytes

(W1177) INVESTIGATING RETINAL TAU PATHOLOGY IN FRONTOTEMPORAL DEMENTIA

(W1178) EXPLORING THE STATISTICS BEHIND PERTURB-SEQ: WHAT IT REVEALS ABOUT COMPLEXBIOLOGICAL PHENOMENA—AND WHAT IT MISSES

(W1179) METABOLIC PROFILING OF VENTRALIZED NEUROECTODERM TO UNDERSTAND HIGH REDOX POTENTIAL OF HUMAN MIDBRAIN DOPAMINERGIC CELLS

(W1180) Modeling PURA syndrome in cerebral organoids using PURA KO and patient iPSCs

(W1181) Multi Organoid Culture System for Recapitulating Liver Pancreas Interaction in Obesity

(W1182) Multi-regional Neural Organoid Panel for Screening of Neurodevelopmental Defects

(W1183) NADPH Oxidase 4 Deficiency Enhances IL-12 Production and Th1 Responses in Mycobacterium tuberculosis Infection through Bone Marrow-Derived Dendritic Cells

(W1184) NEUROGENOMICS STUDY OF STEM CELL-DERIVED NEURAL MODELS IDENTIFIES FUNCTIONAL RISK VARIANTS FOR BRAIN DISORDERS AND IMPLICATES MICROGLIA-SPECIFIC ROLE OF PICALM IN ALZHEIMER'S DISEASE

(W1185) NOVEL MECHANISM OF CYFIP2 INVOLVEMENT IN THE PATHOGENESIS OF DEVELOPMENTAL EPILEPTIC ENCEPHALOPATHY

(W1186) Pathological analysis of age progression using organ organoids derived from aged mice for elucidation of cancer-related disease pathogenesis

(W1187) PRENATAL MeHg EXPOSURE LEADS TO ABERRANT CHOLINERGIC NEURON DEVELOPMENT, POTENTIALLY CONTRIBUTING TO ASD-LIKE BEHAVIOURS

(W1188) PROTEOMIC PROFILING OF ENDURANCE EXERCISE REVEALS INFLAMMATORY AND STEM CELL-ASSOCIATED RESPONSES USING DRIED BLOOD SPOTS

(W1189) RAPID AND CONSISTENT GENERATION OF HUMAN IPSC-DERIVED OLIGODENDROCYTE-LIKE CELLS USING OPTI-OX TECHNOLOGY

(W1191) Rapid, easy, and efficient biallelic knock-in system unified with an independent second synthetic cistron for personalized transgene expression

(W1192) REDUCTION OF THE MITOCHONDRIAL COMPLEX I SUBUNIT AMELIORATES CELL DEATH IN HUMAN IPSC-DERIVED NEURONS

(W1193) RESTORATION OF CALCIUM HANDLING ABNORMALITIES IN BECKER MUSCULAR DYSTROPHY PATIENT-DERIVED INDUCED PLURIPOTENT STEM CELL DIFFERENTIATED CARDIOMYOCYTES WITH GIVINOSTAT TREATMENT

(W1194) NON-CANONICAL ROLES OF THE KEAP1/NRF2 AXIS IN REGULATING QUIESCENCE AND EARLY ACTIVATION IN ADULT MUSCLE STEM CELLS

(W1195) PAXBP1 AND TFIP11 CONTROL EARLY ACTIVATION OF ADULT MUSCLE STEM CELLS VIA THEIR ROLES IN DISTINCT RNA SPLICEOSOMES

(W1196) THE DYNAMIC OF MAMMALIAN PLACENTA METABOLITES AND THEIR IMPACTS ON PLACENTATION, PLACENTAL FUNCTION, AND EMBRYONIC DEVELOPMENT

(W1197) TRANSLATIONAL RESEARCH IN DRUG DISCOVERY TARGETING BRAIN CELLS USING CYNOMOLGUS MONKEY INDUCED PLURIPOTENT STEM CELL-DERIVED ASTROCYTES

(W1198) USING IPSC-DERIVED NEURONS TO INVESTIGATE PATHOGENIC MECHANISMS OF APP-V717I MUTATION IN FAMILIAL ALZHEIMER'S DISEASE

(W1199) A BIPOTENTIAL ORGANOID MODEL OF RESPIRATORY EPITHELIUM RECAPITULATES HIGH INFECTIVITY OF SARS-COV-2 OMICRON VARIANT

(W1200) A Comparative Study of CRISPR-Based In vivo Gene Knock-In Strategies for Haemophilia B Treatment and Editing Outcomes in Genome

(W1201) A HUMAN ELONGATING HEART ORGANOID PLATFORM FOR INVESTIGATING TERATOGEN-INDUCED CONGENITAL HEART DEFECTS

(W1202) A mouse liver tumor-derived organoid platform for understanding driver-dependent liver cancer and response to therapy

(W1203) A Novel Celluar System for Normal Ageing and Anti-ageing Study

(W1204) A novel human fetal lung-derived alveolar organoid model for investigating AT2 cell physiology and disease mechanisms

(W1205) A NOVEL IN VITRO MICROPHYSIOLOGICAL SYSTEM CULTURING DIFFERENT TYPES OF HIPSC-DERIVED PERIPHERAL NEURONS ON MEA FOR NEUROPATHY ASSESSMENT

(W1206) A NOVEL MRNA-LIPID NANOPARTICLE PLATFORM TO RAPIDLY GENERATE FUNCTIONAL FOREBRAIN NEURONS FROM HUMAN PLURIPOTENT STEM CELLS USING NGN2

(W1207) A NOVEL, DSMAD-INDEPENDENT INDUCTION PARADIGM FOR RAPID GENERATION OF HIPSC-DERIVED NEURONS AMENABLE TO REGIONAL PATTERNING

(W1208) A PLATFORM FOR MULTIPLEXED RNA-BASED CELL ENGINEERING TO DRIVE DIFFERENTIATION IN HUMAN STEM CELLS VIA MECHANOPORATION

(W1209) A PLURIPOTENT STEM CELL-DERIVED HIGH THROUGHPUT MODEL OF THE HUMAN NEUROVASCULAR NICHE IN HEALTH AND DISEASE

(W1210) A POTENTIAL REJUVENATION FACTOR C IMPROVES METABOLIC DYSFUNCTIONS AND MITIGATES ATHEROSCLEROSIS IN LDLR -/- MICE

(W1211) A STEPWISE, MODULAR DESIGN OF BUILDING UNIFORM BRAIN ASSEMBLOIDS REPRESENTING THE DYNAMIC CELLULAR INTERPLAY BETWEEN NEURONS AND GLIAL CELLS

(W1212) A STUDY OF SEVERE CATECHOLAMINERGIC POLYMORPHIC VENTRICULAR TACHYCARDIA WITH IPSC-CARDIAC MODEL DERIVED FROM PEDIATRIC PATIENTS

(W1213) AAV-CRISPR-mediated liver-specific knock-in restored hemostasis in neonatal hemophilia B mice

(W1214) ABCA7 DEFICIENCY DISTURBS IMMUNE RESPONSES IN HUMAN IPSC-DERIVED MICROGLIA-LIKE CELLS

(W1215) ADIPONECTIN KNOCKOUT UNVEILED IMPAIRED CELL FATE AND SURVIVAL IN TENDON-DERIVED STEM/PROGENITOR CELLS: INSIGHTS INTO THE PATHOGENESIS OF CHRONIC TENDINOPATHY

(W1216) ADIPOSE-DERIVED STROMAL CELL SECRETOME: A PROMISING CELL-FREE ALTERNATIVE FOR TREATING TENDINOPATHY

(W1217) ADVANCED MODELLING OF UPPER MOTOR NEURON MND PATHOLOGY USING HUMAN PLURIPOTENT STEM CELLS

(W1218) Age-equivalent 3D iN constructs to study age-dependent pathology and resilience mechanisms in Alzheimer’s disease

(W1219) ALLOGENIC MITOCHONDRIA TRANSFER IMPROVES CARDIAC FUNCTION IN IPSC-DIFFERENTIATIED CARDIOMYOCYTES OF A PATIENT WITH BARTH SYNDROME

(W1220) ALMS1 deficient hiPSC derived retinal organoids modeling Alstrom syndrome loss photoreceptors

(W1221) ALTERED GRANULE DYNAMICS IN CDKL5 DEFICIENCY DURING DEVELOPMENT

(W1222) Altered matrix environments enhance the Immunomodulatory Activity of Mesenchymal Stromal/Stem Cells through TNFα/NF-kappa B and TNFα/JNK/AP1 signalling pathways

(W1223) ALZHEIMER'S DISEASE CEREBRAL AND NERUOIMMUNE ORGANOID UNVEILING EARLY AD PATHOLOGIES AND MECHANISMS

(W1224) AMELIORATING SYMPTOMS OF MULTIPLE SCLEROSIS BY TARGETING CD19+ B-CELLS AND SECRETING TGF-β1 USING CAR-MICROGLIA

(W1225) AN IPSC-BASED HIGH THROUGHPUT DRUG SCREENING PLATFORM FOR ALZHEIMER'S DISEASE

(W1226) Analysis of enterovirus A71 intestinal infection using human ES/iPS cells and microphysiological systems

(W1227) APPLICATION OF NEUROMUSCULAR JUNCTION-CHIPS TO CHARACTERIZE SYNAPTIC RNA DYSREGULATION IN ALS

(W1228) APPLICATION OF TONSIL-DERIVED STEM CELL SPHEROID FOR RECOVERING VOLUMETRIC MUSCLE LOSS

(W1229) ASOS TO HERV-K ATTENUATE PRODUCTION OF PHOSPHORYLATED TDP-43 IN IPSC-DERIVED MOTOR NEURONS FROM ALS PATIENTS WITH C9ORF72 EXPANSION

(W1230) AUTOMATED DEVELOPMENT OF IPSC-DERIVED 3D NEURAL ORGANOIDS AND FUNCTIONAL ANALYSIS OF CALCIUM OSCILLATION ACTIVITY

(W1231) BISPHENOL A PROMOTES NEURODEGENERATION VIA EXOSOME-MEDIATED MITOCHONDRIAL DYSFUNCTION

(W1232) BRAIN-SPECIFIC DYSTROPHIN ISOFORMS HAVE A FUNCTION IN RADIAL GLIA DURING HUMAN CEREBRAL ORGANOID DEVELOPMENT

(W1233) BREATHING LIFE INTO STEM CELLS: GENERATING CENTRAL RESPIRATORY NEURONS TO STUDY INVOLUNTARY BREATHING

(W1234) CARDIAC SYMPATHETIC DYSREGULATION IN CATECHOLAMINERGIC POYLMORPHIC VENTRICULAR TACHYCARDIA

(W1235) CATALPOL PROMOTES THE GENERATION OF CEREBRAL ORGANOIDS WITH ORGS THROUGH ACTIVATION OF STAT3 SIGNALING

(W1236) Cell intrinsic and extrinsic of astrocytes lipid metabolism in spinal muscular atrophy

(W1237) CHANGES IN BEHAVIOR, ORGANIZATION, AND STATE OF HIPSC-DERIVED ENDOTHELIAL CELLS EXPOSED TO SHEAR STRESS REVEALED BY LIVE CELL MICROSCOPY AND QUANTIFICATION

(W1238) Characterisation of IPSC-derived Macrophages subtypes in Age-related macular degeneration.

(W1239) CHARACTERISTICS OF ELECTRICAL ACTIVITIES AT SINGLE-CELL RESOLUTION IN HIPSC-DERIVED NEURONS WITH A NOVEL FIELD POTENTIAL IMAGING METHOD ON HD-CMOS-MEA

(W1240) CHARACTERIZATION OF EXTRACELLULAR VESICLES (EVS) DERIVED FROM UMBILICAL CORD MESENCHYMAL STROMAL CELLS (UC-MSCS) LOADED WITH MIR-365A-5P ON CD4+ MEMORY T CELLS

(W1241) CHARACTERIZING AND ELUCIDATING THE ROLE OF SLC35A2 IN HUMAN CORTICAL BRAIN DEVELOPMENT

(W1242) Coiled-Coil Domain-Containing Protein141 is Essential for Cardiomyocyte Development and Function

(W1243) Combing Scalable Organ Chip with Deep-Learning Imaging Analysis for Disease Modeling, Drug Testing, And Precision Medicine

(W1244) COMPREHENSIVE CHARACTERIZATION OF MESENCHYMAL STROMAL CELLS UNVEILS FEATURES PREDICTIVE OF IMMUNE MODULATION CAPACITY

(W1245) Construction of SCA3 Cerebellar Organoid Model and Mechanism of Neuronal Selective Vulnerability

(W1246) CONTINUAL COLLECTION OF CONDITIONED MEDIUM FROM QUIESCENT ADIPOSE TISSUE-DERIVED STROMAL CELLS EMBEDDED IN GELS TO SUPPLY MATERIALS TO ENHANCE WOUND HEALING IN DIABETIC MICE

(W1247) CONVERGENT TRANSCRIPTIONAL DYNAMICS OF MICROGLIA IN THE MOUSE SPINAL CORD DURING AGING AND ALS

(W1248) Cortical Organoids from Induced Pluripotent Stem Cells Exhibit Spiking and Field Potential Activity Reflective of Sleep-like States and Pharmacological Modulation

(W1249) CORTICOSPINAL ASSEMBLOID MODELS REVEAL EARLY TDP-43 PATHOLOGY AND NETWORK DYSFUNCTION IN AMYOTROPHIC LATERAL SCLEROSIS

(W1250) CRAFTING MESENCHYMAL STEM CELL-DERIVED EXTRACELLULAR VESICLES TO CATALYZE THERAPEUTIC BREAKTHROUGHS FOR LIVER DISEASES

(W1251) CRISPR/CAS9 MEDIATED CORRECTION OF GENETIC MUTATIONS IN GBA, VPA35 and LPR10 OF IPSCS FROM PATIENTS WITH PARKINSON’S DISEASE

(W1252) CRISPR-Cas9 Knockout Screening Unveils Essential Genes in Human Trophoblast Differentiation

(W1253) CT PROMOTES SPHEROID FORMATION AND EXTRACELLULAR VESICLE SECRETION OF HUMAN UMBILICAL CORD MESENCHYMAL STEM CELLS AND ITS ROLE IN SKIN INJURY TREATMENT

(W1254) DAMAGE TO BONE MARROW STROMA INDUCED BY GAMMA-RADIATION OF A RECIPIENT IS A PREREQUISITE FOR ENGRAFTMENT OF DONOR’S MSCS INJECTED INTRAVENOUSLY

(W1255) DECIPHERING RETINOBLASTOMA TUMORIGENESIS WITH RB1 KNOCKOUT CONE REPORTER RETINAL ORGANOIDS

(W1256) DECIPHERING THE ROLE OF TUBULIN ISOFORMS IN NEURODEGENERATION AND AGEING

(W1257) DECRYPTING THE IMPACT OF DEFECTIVE PRDM13 DURING CEREBELLAR AND SPINAL DEVELOPMENT IN HUMAN-BASED ORGANOID MODEL

(W1258) Deficiency of astrocyte lipid metabolism contributes to spinal muscular atrophy

(W1259) Defining the molecular basis of cardiomyopathy using human pluripotent stem cell models

(W1260) DELINEATING THE NEUROBIOLOGICAL MECHANISMS INVOLVED IN SETBP1-HAPLOINSUFFICIENCY DISORDER USING HUMAN NEURAL ORGANOIDS AND TRANSCRIPTOMICS

(W1261) DERIVATION OF HUMAN POST-MITOTIC CARDIOMYOCYTES FROM TETRAPLOID INDUCED PLURIPOTENT STEM CELLS

(W1262) DERIVATION, CHARACTERIZATION AND CRYOPRESERVATION OF PRIMARY HUMAN FETAL ORGANOIDS FROM SECOND AND THIRD TRIMESTER AMNIOTIC FLUID

(W1263) Development and Characterization of Chicken Lung Organoids with Prospects of Modeling Highly Pathogenic Avian Influenza In Vitro

(W1264) DEVELOPMENT OF A DRUG NEUROTOXICITY EVALUATION PLATFORM USING NEURAL ORGANOIDS AND MACHINE LEARNING

(W1265) DEVELOPMENT OF A FULLY HUMAN GLIOBLASTOMA-IN-BRAIN-SPHEROID MODEL FOR ACCELERATED TRANSLATIONAL RESEARCH

(W1266) DEVELOPMENT OF A LIVER-ON-A-CHIP MODEL TO SIMULATE LIVER INFLAMMATORY RESPONSE

(W1267) DEVELOPMENT OF AN HD-CMOS–MEA–BASED METHOD FOR CARDIOTOXICITY DETECTION AND MECHANISM-OF-ACTION PREDICTION IN HUMAN IPSC-DERIVED CARDIOMYOCYTES USING BEAT PROPAGATION PATTERNS

(W1268) DEVELOPMENT OF MICROFABRICATED DEVICES FOR IN VITRO RECONSTRUCTION OF SENSORY NEURAL NETWORKS INDUCING HYPERSYNCHRONY BY STIMULATION OF SINGLE NEURONS

(W1269) DIFFERENTIAL RESPONSE OF INDUCED PLURIPOTENT STEM CELL-DERIVED CARDIOMYOCYTES TO CHRONIC BETA-ADRENERGIC STIMULATION AND ELECTRICAL PACING IN A MODEL OF EXERCISE-INDUCED LONG QT SYNDROME

(W1270) DIRECT REPROGRAMMING OF URINE CELLS INTO CRANIAL NEURAL CREST-LIKE CELLS

(W1271) DIVERGING AND CONVERGING MECHANISMS IN POLYQ-RELATED DISEASES

(W1272) Dysregulation of methionine metabolism of hepatocytes induced epithelial-mesenchymal transition of hepatocytes and abnormal growth of cholangiocytes in biliary atresia

(W1273) EFFECT OF EXTRACELLULAR VESICLES DERIVED FROM GLYCOLYTIC MESENCHYMAL STEM/STROMAL CELLS ON THE PHENOTYPIC AND METABOLIC REPROGRAMMING OF SYNOVIAL MACROPHAGES IN PATIENTS WITH OSTEOARTHRITIS

(W1274) EFFECTS OF A NATURAL COMPOUND ON CARDIOMYOCYTE DIFFERENTIATION OF INDUCED PLURIPOTENT STEM CELLS FROM A PATIENT WITH BARTH SYNDROME

(W1275) Effects of bacteriophages on stem cells

(W1276) ELECTROPHYSIOLOGY AND MOLECULAR PHENOTYPE SCREENING PLATFORM FOR THE DEVELOPMENT OF NEW RETT SYNDROME THERAPIES

(W1277) ELUCIDATION OF THE MECHANISMS OF CARDIOMYOPATHY BY USING HUMAN IPS CELL-DERIVED CARDIOMYOCYTES FROM FUKUYAMA MUSCULAR DYSTROPHY PATIENTS

(W1278) ENDOTHELIAL PRMT1 IS ESSENTIAL FOR VASCULAR REGENERATION AND CARDIAC REPAIR POST MYOCARDIAL INFARCTION

(W1279) ENGINEERING ANTIBODY-CAR-MACROPHAGES (AB-CAR-M) FOR TUMOR MICROENVIORNMENT REMODELLING (EATER)

(W1280) ENGINEERING HUMAN GLOMERULUS-ON-A-CHIP USING HUMAN INDUCED PLURIPOTENT STEM CELLS

(W1281) Engineering splicing-regulatory networks to produce mature stem cell-derived neurons

(W1282) ENHANCED ALZHEIMER'S DISEASE MODELING: IPSC-DERIVED CHOLINERGIC NEURONS AND CRISPR-CAS9 APPROACH

(W1283) EPIGENETIC MEMORY AND INFLAMMATORY PROFILING OF ADIPOCYTES DIFFERENTIATED FROM UMBILICAL CORD MSCS IN OBESITY

(W1284) Establishing a functional standard for hiPSC-derived cardiomyocyte electrophysiology using the MEA assay

(W1285) ESTABLISHING AN INDUCED PLURIPOTENT STEM CELL BANK FROM URINE CELLS OF PEDIATRIC NEUROGENETIC DISEASE PATIENTS

(W1286) Establishing reliable QC measures for iPSC-derived microglia ensuring robust and reproducible pharmacology studies.

(W1287) ESTABLISHMENT OF AN NMOSD RODENT MODEL WITH DISTINCT PATHOLOGICAL CHARACTERISTICS FROM EAE MODEL

(W1288) ESTABLISHMENT OF HUMAN IPSC-DERIVED CORTICAL ORGANOIDS TO MODEL H3.3 G34R PEDIATRIC HIGH-GRADE GLIOMA

(W1289) ESTABLISHMENT OF IMPLANTATION MODEL WITH HUMAN EXPANDED POTENTIAL STEM CELL DERIVED EMBRYO SURROGATE AND OPEN-FACED ENDOMETRIAL LAYER FOR STUDYING IMPLANTATION IN IVF PATIENTS

(W1290) Estradiol in promoting the repopulation of transplanted hepatocytes

(W1291) Evaluation of Botulism Neurotoxin Exposure in a Human hPSC-Derived Neuromuscular Junction Platform

(W1292) EVS FROM GLYCOLYTIC MSCS: A PROMISING THERAPY FOR OSTEOARTHRITIS

(W1293) EXPANDED POTENTIAL STEM CELL-DERIVED SKIN ORGANOIDS FOR STAT1-GOF DISEASE MODELING

(W1294) EXPLORING AN ANTIRETROVIRAL DRUG DELIVERY RESEARCH TOOL USING HIV-INFECTED BLOOD BRAIN BARRIER COMPONENTS DERIVED FROM HUMAN INDUCED PLURIPOTENT STEM CELLS

(W1295) EXPLORING HORMONAL AND INTESTINAL ADAPTATIONS DURING PREGNANCY USING INTESTINAL ORGANOID MODELS

(W1296) EXPLORING IN VITRO PHENOTYPIC VARIABILITY IN DIGEORGE SYNDROME THROUGH HIPSC MODEL

(W1297) EXPLORING MYELINATION DYNAMICS IN 2D AND 3D MODELS USING HUMAN INDUCED PLURIPOTENT STEM CELL-DERIVED OLIGODENDROCYTE PROGENITORS

(W1298) EXPLORING THE HEART-KIDNEY CROSSTALK IN VITRO: THE IMPACT OF KIDNEY DAMAGE ON CARDIAC FUNCTION USING ORGANOIDS

(W1299) EXPLORING THE IMPACT OF HEPATIC FIBROGENESIS ON GAP JUNCTIONS: A MULTICELLULAR SPHEROID MODEL APPROACH

(W1300) EXPLORING THE MOLECULAR AND FUNCTIONAL EFFECTS OF STIMULATION ON PSC-DERIVED SPINAL INTERNEURONS

(W1301) EXPLORING THE ROLE OF NOTCH SIGNALING IN PATHOLOGICAL OSTEOGENIC DIFFERENTIATION DURING CALCIFIC AORTIC VALVE DISEASE

(W1302) EXPOSURE TO 2,3,7,8-TETRACHLOROBENZO-P-DIOXIN ALTERED THE DNA METHYLATION PATTERNS OF GERMLINE DEVELOPMENTAL GENES IN HUMAN EMBRYONIC STEM CELLS

(W1303) FUNCTIONAL MATURATION OF HUMAN IPSC-DERIVED MODELS OF THE ENTERIC NERVOUS SYSTEM

(W1304) Functional rescue of neurons derived from iPSCs of GGC repeat disease patients using Cytosine Base Editor

(W1305) FUNCTIONALLY RELEVANT PSC-DERIVED HEPATOCYTES AND LIVER ORGANOIDS FOR HEPATOTOXICITY AND LIVER BIOLOGY MODELING

(W1306) G3BP1 LOSS ENHANCES AMYLOIDOGENIC mRNA STABILITY AND DRIVES AMYLOID-β AGGREGATION IN IRRADIATION-INDUCED SENESCENT HUMAN ASTROCYTES

(W1307) Gel-free engineered heart tissue for dual excitation-contraction recording and disease modelling.

(W1308) GENE REPLACEMENT USING WILD-TYPE TNNT2 RESCUES THE PHENOTYPES OF IPSC-CARDIOMYOCYTES DERIVED FROM PEDIATRIC DILATED CARDIOMYOPATHY HARBORING THE TNNT2-R151W MUTATION.

(W1310) GENERATION OF INDUCED PLURIPOTENT STEM CELLS FOR USHER SYNDROME MODEL

(W1311) GENERATION OF IPSC LINES FROM PATIENTS WITH BARDET BIEDL SYNDROME AND STARGARDT DISEASE AS IN VITRO HUMAN MODELS OF INHERITED RETINAL DYSTROPHY

(W1312) Generation of iPSC-derived human venous endothelial cells for the modeling of vascular malformations and drug discovery

(W1313) GENERATION OF IPSCS LINE FROM PATIENT WITH SINGLETON-MERTEN SYNDROME

(W1314) GENERATION OF TETRAPLOID CARDIOMYOCYTES BY FUSION OF DIPLOID IPSC LINES DERIVED FROM TWO DIFFERENT INDIVIDUALS

(W1316) Solving challenging Titinopathy cases via multi-omics and iPSCs

(W1317) HAPLOINSUFFICIENCY IN HUMAN NEURAL PROGENITOR CELLS: IMPLICATION FOR AUTISM SYNDROME DISORDERS

(W1318) Harnessing SMSER: A High-Throughput Platform for Programming Macrophages

(W1319) HCMV INFECTION OF MACROPHAGES INDUCES INFLAMMATION BY UPREGULATING IL-6/IL-6ST SIGNALING IN CHOLANGIOCYTES IN BILIARY ATRESIA

(W1320) HDAC11-Mediated STAT3 Activation Drives Inflammation and Endothelial Dysfunction in Diabetic iPS-ECs

(W1321) HEMATOPOIETIC STEM CELL-DERIVED CAR MACROPHAGES REMODEL TUMOR NICHE

(W1322) High-Purity Functional Corneal Endothelial Cells from Human Induced Pluripotent Stem Cells via a Novel Wash-Out Method

(W1323) HIPSCS-DERIVED IN VITRO MODELS OF THE BLOOD-BRAIN BARRIER FOR STUDYING NANOPARTICLE TRANSPORT

(W1324) Homology-independent targeted insertion-mediated derivation of M1-biased macrophages harboring Megf10 and CD3ζ from human pluripotent stem cells

(W1325) HUMAN AIRWAY AND NASAL ORGANOIDS REVEAL ESCALATING REPLICATIVE FITNESS OF SARS-COV-2 EMERGING VARIANTS

(W1326) HUMAN AIRWAY ORGANOIDS COMBINED WITH LUNG EXTRACELLULAR MATRIX FOR FIBROTIC DISEASE MODELING

(F1336) HUMAN NEURAL STEM CELL-DERIVED EXTRACELLULAR VESICLES ALLEVIATES BREAST CANCER CHEMOTHERAPY-INDUCED COGNITIVE IMPAIRMENTS

(W1327) A NOVEL STEM CELL PLATFORM FOR ANTI-MONKEYPOX VIRUS STRATEGIES

(W1328) HUMAN PLURIPOTENT STEM CELL-DERIVED NEUROMUSCULAR ORGANOID: A PLATFORM FOR WASTING SYNDROME RESEARCH

(W1329) HUMAN TROPHOBLAST CELLULAR MODEL IS HIGHLY PERMISSIVE TO SARS-COV-2 INFECTION AND ENABLES THE DISCOVERY OF ANTIVIRAL NATURAL COMPOUNDS POTENTLY AGAINST SARS-COV-2

(W1330) HYPOIMMUNOGENIC HUMAN MOTOR NEURONS INDUCED FROM IPSCS IN VIVO SUBSTANTIALLY AMELIORATE ALS DISEASE

(W1331) Hypoxic conditioning rescues retinal precursor cells from CoCl2-induced ferroptosis via Drp1 and Vdac1.

(W1332) Identification and mitigation of major confounders in psychiatric disease models: clonal, batch-to batch, operator- and material-based variability

(W1333) IDENTIFICATION OF A LONG-TERM SURVIVING HUMAN MESENCHYMAL STROMAL CELL SUBPOPULATION UPON INTRADERMAL INJECTION IN IMMUNODEFICIENT MICE

(W1334) IDENTIFICATION OF CIRCULATING MICRORNA SIGNATURES IN ANTHRACYCLINE-INDUCED CARDIAC INJURY USING IPSC-DERIVED CARDIOMYOCYTES

(W1335) IDENTIFICATION OF NEURON-GLIA SIGNALING FEEDBACK IN HUMAN SCHIZOPHRENIA USING PATIENT-DERIVED, MIX-AND-MATCH FOREBRAIN ASSEMBLOIDS

(W1336) IDENTIFYING PROTECTIVE FACTORS AND UNRAVELING THE MOLECULAR MECHANISMS THAT PRESERVE OCULOMOTOR NEURONS FROM DEGENERATION IN PATIENTS WITH SPINAL MUSCULAR ATROPHY

(W1337) IMMUNE PHENOTYPE OF IPSC-DERIVED ASTROCYTES FROM PATIENTS WITH SPINOCEREBELLAR ATAXIA TYPE 17

(W1338) IN SILICO AND IN VITRO IDENTIFICATION OF ANTI-MICROBIAL PEPTIDES IN SYNERGY WITH MESENCHYMAL STROMAL CELLS AGAINST UROPATHOGENIC ESCHERICHIA COLI (UPEC).

(W1339) IN VITRO DISEASE MODELING OF FTLD USING PATIENT-DERIVED IPSCS IDENTIFIED POTENTIAL THERAPEUTIC AGENTS AND CELLULAR/MOLECULAR MECHANISMS.

(W1340) In Vitro Human Neurovascular Unit Model Using Cells Differentiated from a Single iPSC Lineage for Metabolic and Neurodegenerative Diseases Research

(W1341) INDUCED PLURIPOTENT STEM CELL-DERIVED MESENCHYMAL STEM CELLS IMPROVE CARDIAC FUNCTION THROUGH EXTRACELLULAR VESICLE-MEDIATED TISSUE REPAIR IN A RAT ISCHEMIC CARDIOMYOPATHY MODEL

(W1342) INDUCTION OF ALPHA-SYNUCLEIN PATHOLOGY IN HUMAN IPSC-DERIVED NEUROSPHEROIDS TO MODEL SYNUCLEINOPATHIES

(W1343) INHIBITION OF SENESCENCE IN PROGERIA SKIN FIBROBLASTS CULTURED IN XENO-FREE MEDIA

(W1344) Innovative Fluorescent Dye for RNA Binding in Adult Mesenchymal Stem Cells

(W1345) INTERACTION BETWEEN SYMPATHETIC NEURONS AND CARDIOMYOCYTES IN A PATIENT-SPECIFIC INDUCED PLURIPOTENT STEM CELL TAKOTSUBO-MODEL

(W1346) INTESTINAL ORGANOID MODEL TO EXPLORE NOVEL LATE-STAGE THERAPEUTIC STRATEGIES FOR RESTORING CHOLERA-INDUCED INTESTINAL DAMAGE

(W1347) INVESTIGATING FAN1 AS A GENETIC MODIFIER OF RETT SYNDROME IN HUMAN STEM CELL-DERIVED NEURAL PRECURSOR CELLS AND DORSAL FOREBRAIN ORGANOIDS

(W1348) INVESTIGATING GLP-1 RECEPTOR AGONISTS AS A NOVEL THERAPEUTIC APPROACH FOR PARKINSON’S DISEASE USING PATIENTS IPSCS-DERIVED MIDBRAIN ORGANOIDS

(W1349) INVESTIGATING SARS-COV-2 SPIKE VARIANTS IN PSC-DERIVED CARDIOMYOCYTES FOR EARLY CARDIAC DEVELOPMENT

(W1350) INVESTIGATING THE BIOLOGICAL PROPERTIES OF CIRCULATING HEMATOPOIETIC STEM/PROGENITOR CELLS IN PEDIATRIC SUBJECTS AS NOVEL SOURCE FOR GENE THERAPY.

(W1351) INVESTIGATING THE EARLY CELLULAR CHANGES ASSOCIATED WITH LRRK2 G2019S MUTATION

(W1363) CRISPR-READY ioGLUTAMATERGIC NEURONS FOR VERSATILE GENE MODULATION AND DRUG TARGET DISCOVERY

(W1364) AI-ENABLED AUTOMATION OF 3D ORGANOID CULTURE